UP21 began as a group of mothers who had a goal to educate the community about the abilities of individuals with Down Syndrome. It is a non-profit 501(c)3 organization whose mission is to provide support, resources and education to families of individuals with Down syndrome and the community to foster an environment in which individuals with Down syndrome achieve their full potential in their community. Many of the UP21 team have children who participate in Miracle League Northshore's sports leagues and they are excited to support the League's motto that "every child deserves the chance to play" by participating in Radio-thon 2021.